SSB anticorps
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- Antigène Voir toutes SSB Anticorps
- SSB (Sjogren Syndrome Antigen B (SSB))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SSB est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of SSB protein.
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity chromatography using epitope-specific immunogen
- Pureté
- > 95 % (by SDS-PAGE)
- Top Product
- Discover our top product SSB Anticorps primaire
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- Indications d'application
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- SSB (Sjogren Syndrome Antigen B (SSB))
- Autre désignation
- SS-B / La (SSB Produits)
- Synonymes
- anticorps LARP3, anticorps La, anticorps lab1, anticorps larp3, anticorps ssb, anticorps Mt-SSB, anticorps MtSSB, anticorps Ssbp1, anticorps SS-B, anticorps laa-a, anticorps ssb-a, anticorps ssb-b, anticorps wu:fb17f11, anticorps zgc:55588, anticorps Sjogren syndrome antigen B, anticorps Sjogren syndrome antigen B L homeolog, anticorps single stranded DNA binding protein 1, anticorps Sjogren syndrome antigen B S homeolog, anticorps Sjogren syndrome antigen B (autoantigen La), anticorps SSB, anticorps ssb.L, anticorps SSBP1, anticorps Ssb, anticorps ssb.S, anticorps ssb
- Sujet
- Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B and C complex, thereby mediating protein degradation. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. SSB-2 (SplA/ryanodine (SPRY) receptor domain-containing SOCS box protein 2), also known as GGRCC9 (gene-rich cluster protein C9), SPSB2 or MGC2519, is a cytoplasmic protein belonging to the SPSB family of proteins that contain a central SPRY domain and a C-terminal SOCS box. The SPRY domain is believed to be a protein-protein interaction motif. Members of the SPSB family are capable of interacting with Met (a receptor for hepatocyte growth factors (HGFs)), and SSB-1 is known to promote HGF signaling. SSB-1, SSB-2 and SSB-4 are also able to interact with PAR4 (prostate apoptosis response protein 4). Mutations in the genes encoding SPSB proteins are associated with several human diseases.Synonyms: LARP3, La autoantigen, La ribonucleoprotein, Lupus La protein, SSB, Sjoegren syndrome type B antigen
- Poids moléculaire
- approx. 50 kDa
- ID gène
- 6741
- NCBI Accession
- NP_003133
- UniProt
- P05455
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