Stathmin 1 anticorps

N° du produit ABIN498615

Détail du produit anti-Stathmin 1 anticorps

Antigène: Stathmin 1 (STMN1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Stathmin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Op18 protein. (region surrounding Val31)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur Stathmin 1

Antigène: Stathmin 1 (STMN1)

Autre désignation: Stathmin / STMN1 (STMN1 Produits)

Synonymes: anticorps C1orf215, anticorps LAP18, anticorps Lag, anticorps OP18, anticorps PP17, anticorps PP19, anticorps PR22, anticorps SMN, anticorps 19k, anticorps Lap18, anticorps Op18, anticorps P18, anticorps P19, anticorps Pig, anticorps Pp17, anticorps Pp18, anticorps Pp19, anticorps Pr22, anticorps Smn, anticorps prosolin, anticorps op18, anticorps stathmin, anticorps stmn1, anticorps stmn1a, anticorps lag, anticorps lap18, anticorps pp17, anticorps pp19, anticorps pr22, anticorps smn, anticorps fj43c10, anticorps wu:fj38b07, anticorps wu:fj43c10, anticorps zgc:110159, anticorps cb959, anticorps wu:fb14e04, anticorps zgc:136942, anticorps stmn1-a, anticorps stmn1b, anticorps xo35, anticorps stathmin 1, anticorps stathmin 1 S homeolog, anticorps stathmin 1b, anticorps stathmin 1a, anticorps stathmin-like, anticorps stathmin, anticorps stathmin 1 L homeolog, anticorps STMN1, anticorps Stmn1, anticorps stmn1.S, anticorps stmn1, anticorps stmn1b, anticorps stmn1a, anticorps LOC100229194, anticorps stmn1.L

Sujet: Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phosphorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation. Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.Synonyms: LAP18, Leukemia-associated phosphoprotein p18, Metablastin, OP18, Oncoprotein 18, Op18, Phosphoprotein p19, Prosolin, Protein Pr22, pp17, pp19

Poids moléculaire: approx. 19 kDa

ID gène: 3925

NCBI Accession: NP_005554

UniProt: P16949

Pathways: Signalisation MAPK, Dynamique des Microtubules