RPSA/Laminin Receptor anticorps

N° du produit ABIN498680

Détail du produit anti-RPSA/Laminin Receptor anticorps

Antigène: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPSA/Laminin Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Laminin-R protein. (region surrounding Gln215)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RPSA/Laminin Receptor

Antigène: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Autre désignation: RPSA (RPSA Produits)

Synonymes: anticorps 37LRP, anticorps 67LR, anticorps LBP/p40, anticorps LRP/LR, anticorps LamR, anticorps rpsa, anticorps LamR1, anticorps RPSA, anticorps LAMBR, anticorps LAMR1, anticorps LBP, anticorps LRP, anticorps NEM/1CHD4, anticorps SA, anticorps lamR, anticorps p40, anticorps 67kDa, anticorps 67lr, anticorps AL022858, anticorps Lamr, anticorps Lamr1, anticorps Lamrl1, anticorps MLR, anticorps P40, anticorps P40-3, anticorps P40-8, anticorps lamr1, anticorps zgc:55831, anticorps zgc:77824, anticorps DMRT1, anticorps 40S ribosomal protein SA, anticorps 67kD laminin receptor, anticorps ribosomal protein SA, anticorps rssa, anticorps rpsa, anticorps RPSA, anticorps Rpsa, anticorps LOC100144340

Sujet: Laminin receptor (Laminin-R) has a heterodimeric structure similar to that of receptors for other extracellular matrix proteins such as Fibronectin and Vitronectin. Incorporation of Laminin-R into lysosomal membranes makes it possible for lysosomes to attach to surfaces coated with Laminin. This and other properties identify Laminin-R as a member of the integrin family of cell adhesion receptors. The Laminin-R precursor is a polypeptide whose expression is consistently upregulated in aggressive carcinoma. The precursor, which is also identified as p40 ribosome-associated protein, appears to be a multifunctional protein involved in the translational machinery. Laminin-R (also known as colon carcinoma Laminin-binding protein) is found at nine-fold higher levels in colon carcinoma than in adjacent normal colonic epithelium. Addi-tionally, the level of the Laminin-R is higher in the lung cancer cell line than in the lung cell line.Synonyms: 37 kDa laminin receptor precursor, 37/67 kDa laminin receptor, 37LRP, 40S ribosomal protein SA, 67 kDa laminin receptor, 67LR, Colon carcinoma laminin-binding protein, LAMBR, LAMR1, LRP/LR, LamR, Laminin receptor 1, Laminin-binding protein precursor p40, NEM/1CHD4

Poids moléculaire: approx. 40 kDa

ID gène: 3921

NCBI Accession: NP_001012321

UniProt: P08865

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly