Cyclin E2 anticorps

N° du produit ABIN498694

Détail du produit anti-Cyclin E2 anticorps

Antigène: Cyclin E2 (CCNE2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin E2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Cyclin E2 protein. (region surrounding asn387)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Cyclin E2

Antigène: Cyclin E2 (CCNE2)

Autre désignation: Cyclin E2 (CCNE2 Produits)

Synonymes: anticorps ccne2, anticorps MGC53684, anticorps MGC132360, anticorps cb165, anticorps sb:cb165, anticorps zgc:86724, anticorps CCNE2, anticorps cyce2, anticorps CYCE2, anticorps cyclin E2, anticorps cyclin E2 L homeolog, anticorps cyclin E1 L homeolog, anticorps CCNE2, anticorps ccne2.L, anticorps ccne2, anticorps ccne1.L, anticorps Ccne2

Sujet: Cyclin E, along with the three cyclin D proteins and cyclin C, has been shown to represent a putative G1 cyclin on the basis of its cyclic pattern of mRNA expression, with maximal levels being detected near the G1/S boundary. cyclin E has been found to be associated with the transcription factor E2F in a temporally regulated manner. Cyclin E2 is a cyclin E-related protein that specifically interacts with Cdk2 and Cdk3 and with p27 and p21. Cyclin E2 expression peaks at the G1/S phase transition of the cell cycle, in parallel with cyclin E. Whereas cyclin E1 is expressed in most proliferating normal and tumor cells, cyclin E2 levels are low or undetectable in nontransformed cells, and are elevated in tumor-derived cells.Synonyms: CCNE2, Cyclin-E2, G1/S-specific cyclin-E2

Poids moléculaire: approx. 46 kDa

ID gène: 9134

NCBI Accession: NP_477097

UniProt: O96020

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases