RAD51 anticorps

N° du produit ABIN498997

Détail du produit anti-RAD51 anticorps

Antigène: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: This antibody detects endogenous levels of Rad51 protein. (region surrounding Thr309)

Réactivité croisée (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RAD51

Antigène: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Autre désignation: RAD51 (RAD51 Produits)

Synonymes: anticorps BRCC5, anticorps HRAD51, anticorps HsRad51, anticorps HsT16930, anticorps MRMV2, anticorps RAD51A, anticorps RECA, anticorps CRAD51, anticorps wu:fb38e12, anticorps zgc:77754, anticorps RGD1563603, anticorps ATRAD51, anticorps F22D1.20, anticorps F22D1_20, anticorps RAS associated with diabetes protein 51, anticorps AV304093, anticorps Rad51a, anticorps Reca, anticorps brcc5, anticorps rad51, anticorps rad51a, anticorps reca, anticorps xrad51, anticorps RAD51 recombinase, anticorps RAS associated with diabetes protein 51, anticorps RAD51 recombinase L homeolog, anticorps RAD51, anticorps rad51, anticorps Rad51, anticorps rad51.L

Sujet: Rad51 is a recombinase that is essential for homologous recombination and double-strand break repair. It binds to single and double-stranded DNA, and has DNA-dependent ATPase activity. Rad51 unwinds duplex DNA and forms helical nucleoprotein filaments in a manner that is controlled through the action of DNA helicases that counteract nucleofilament formation. Rad51 interacts with BRCA1 and BRCA2, and also plays a role in p53-mediated signalling. Interaction of Rad51 with Chk1 kinase may occur in response to Chk1 phosphorylation.Synonyms: DNA repair protein RAD51 homolog 1, RAD51A, RECA

Poids moléculaire: approx. 42 kDa

ID gène: 5888

NCBI Accession: NP_002866

UniProt: Q06609

Pathways: Réparation de l'ADN