EPH Receptor A5 anticorps (AA 451-550) (Alexa Fluor 750)
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- Antigène Voir toutes EPH Receptor A5 (EPHA5) Anticorps
- EPH Receptor A5 (EPHA5)
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Épitope
- AA 451-550
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EPH Receptor A5 est conjugé à/à la Alexa Fluor 750
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Cow,Pig,Rabbit,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human EphA5/Eph receptor A5
- Isotype
- IgG
- Top Product
- Discover our top product EPHA5 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- EPH Receptor A5 (EPHA5)
- Autre désignation
- Eph receptor A5 (EPHA5 Produits)
- Synonymes
- anticorps CEK7, anticorps EHK-1, anticorps EHK1, anticorps EK7, anticorps HEK7, anticorps TYRO4, anticorps AI854630, anticorps AW125296, anticorps Cek7, anticorps Ehk1, anticorps Els1, anticorps Hek7, anticorps Rek7, anticorps bsk, anticorps Els1., anticorps EPHA5, anticorps EPH receptor A5, anticorps Eph receptor A5, anticorps EPHA5, anticorps epha5, anticorps Epha5
- Sujet
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Synonyms: EK7, CEK7, EHK1, HEK7, EHK-1, TYRO4, Ephrin type-A receptor 5, Brain-specific kinase, EPH homology kinase 1, EPH-like kinase 7, EPHA5, BSK
Background: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity).
- ID gène
- 2044
- UniProt
- P54756
- Pathways
- Signalisation RTK
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