HDAC3 anticorps (pSer424) (Alexa Fluor 680)

N° du produit ABIN5004345

Détail du produit anti-HDAC3 anticorps (Alexa Fluor 680)

Antigène: HDAC3 (Histone Deacetylase 3 (HDAC3))

Épitope: pSer424

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC3 est conjugé à/à la Alexa Fluor 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human HDAC3 around the phosphorylation site of Ser424

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HDAC3

Antigène: HDAC3 (Histone Deacetylase 3 (HDAC3))

Autre désignation: HDAC3 (HDAC3 Produits)

Synonymes: anticorps CG2128, anticorps DHDAC3, anticorps DmHDAC3, anticorps Dmel\\CG2128, anticorps Dromel_CG2128_FBtr0078767_hdac3_mORF, anticorps HDAC, anticorps HDAC3, anticorps Hdac 3, anticorps dHDAC3, anticorps dmHDA402, anticorps hdac3, anticorps HDm, anticorps hd3, anticorps RPD3, anticorps XRpd3, anticorps rpd3-2, anticorps HD3, anticorps RPD3-2, anticorps AW537363, anticorps zgc:55927, anticorps Histone deacetylase 3, anticorps histone deacetylase 3, anticorps histone deacetylase 3 S homeolog, anticorps HDAC3, anticorps hdac3, anticorps CNL05260, anticorps Hdac3, anticorps hdac3.S

Sujet:

Synonyms: HDAC3 phospho S424, HDAC3 phospho Ser424, p-HDAC3 Ser424, RPD3 2, RPD3-2, HD 3, HD3, HDAC 3, Histone deacetylase 3 HD3 RPD3-2, histone deacetylase 3, RPD 3, RPD3, SMAP 45, SMAP-45, SMAP45, HDAC3_HUMAN.

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008].

ID gène: 8841

Pathways: Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development