IL-37 anticorps

N° du produit ABIN5027737

Détail du produit anti-IL-37 anticorps

Antigène: IL-37 (IL37) (Interleukin 37 (IL37))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-37 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: Full length recombinant IL-37 protein was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 2-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur IL-37

Antigène: IL-37 (IL37) (Interleukin 37 (IL37))

Autre désignation: IL-37 (IL37 Produits)

Synonymes: anticorps FIL1, anticorps FIL1(ZETA), anticorps FIL1Z, anticorps IL-1F7, anticorps IL-1H, anticorps IL-1H4, anticorps IL-1RP1, anticorps IL-37, anticorps IL1F7, anticorps IL1H4, anticorps IL1RP1, anticorps interleukin 37, anticorps IL37

Sujet: IL-37 (Interleukin-37) is a member of IL-1 family and is primarily an anti-inflammatory cytokine, which reduces systemic and local inflammation. There are five different splice variants of IL-37 termed IL-37a-e, where Isoform IL-37b is the largest isoform. IL-37 has significant sequence similarity with IL-18 and highly expressed in inflammatory tissues, which inhibits the excessive inflammatory response. The expression is highly induced by several toll-like receptor (TLR) ligands and pro-inflammatory cytokines such as IL-1beta, TNF-alpha, IFN-gamma. IL-37 is a potent inhibitor of innate immunity by shifting the cytokine equilibrium away from excessive inflammation.

Poids moléculaire: 20 kDa

ID gène: 27178

UniProt: Q9NZH6