EPM2A anticorps (AA 243-331)

N° du produit ABIN533790

Détail du produit anti-EPM2A anticorps

Antigène: EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))

Épitope: AA 243-331

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EPM2A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Fonction: Mouse monoclonal antibody raised against partial recombinant EPM2A.

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: Recombinant protein corresponding to amino acids 243-331 of human EPM2A.

Clone: K2A3

Isotype: IgG1

Information d'application

Indications d'application: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS, pH 7.4 (10 % glycerol, 0.02 % sodium azide).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-EPM2A (ABIN533790)

Tagliabracci, Turnbull, Wang, Girard, Zhao, Skurat, Delgado-Escueta, Minassian, Depaoli-Roach, Roach: "Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 49, pp. 19262-6, (2007) (PubMed).

Wang, Parker, Skurat, Raben, DePaoli-Roach, Roach: "Relationship between glycogen accumulation and the laforin dual specificity phosphatase." dans: Biochemical and biophysical research communications, Vol. 350, Issue 3, pp. 588-92, (2006) (PubMed).

Ganesh, Delgado-Escueta, Suzuki, Francheschetti, Riggio, Avanzini, Rabinowicz, Bohlega, Bailey, Alonso, Rasmussen, Thomson, Ochoa, Prado, Medina, Yamakawa: "Genotype-phenotype correlations for EPM2A mutations in Lafora's progressive myoclonus epilepsy: exon 1 mutations associate with an early-onset cognitive deficit subphenotype." dans: Human molecular genetics, Vol. 11, Issue 11, pp. 1263-71, (2002) (PubMed).

Détails sur EPM2A

Antigène: EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))

Autre désignation: Laforin (EPM2A Produits)

Synonymes: anticorps TG-B, anticorps Tg(TcraK,TcrbK)TG-BFlv, anticorps EPM2, anticorps MELF, anticorps laforin, anticorps EPM2A, laforin glucan phosphatase, anticorps epilepsy, progressive myoclonic epilepsy, type 2 gene alpha, anticorps EPM2A, anticorps Epm2a

ID gène: 7957

Pathways: Cellular Glucan Metabolic Process