Survivin anticorps

N° du produit ABIN534089

Détail du produit anti-Survivin anticorps

Antigène: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Survivin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Fonction: Mouse monoclonal antibody raised against full length recombinant BIRC5.

Specificité: This antibody is specific to the cytoplasmic form of survivin. The epitope recognized is between amino acids 57-67.

Réactivité croisée: Humain, Souris, Rat

Immunogène: Recombinant protein corresponding to full length human BIRC5.

Clone: 60-11

Isotype: IgG2a

Information d'application

Indications d'application: Immunocytochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-Survivin (ABIN534089)

Brocardo, Lei, Tighe, Taylor, Mok, Henderson: "Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: regulation of Bcl-2 and implications for cell survival." dans: The Journal of biological chemistry, Vol. 283, Issue 9, pp. 5950-9, (2008) (PubMed).

Lechler, Wu, Bernhardt, Campean, Gastiger, Hackenbeck, Klanke, Weidemann, Warnecke, Amann, Engehausen, Willam, Eckardt, Rödel, Wiesener: "The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney." dans: The American journal of pathology, Vol. 171, Issue 5, pp. 1483-98, (2007) (PubMed).

Ryan, ODonovan, Browne, OShea, Crown, Hill, McDermott, OHiggins, Duffy: "Expression of survivin and its splice variants survivin-2B and survivin-DeltaEx3 in breast cancer." dans: British journal of cancer, Vol. 92, Issue 1, pp. 120-4, (2005) (PubMed).

Xu, Zhao, Ding, Tran, Zhang, Pandolfi, Chang: "Promyelocytic leukemia protein 4 induces apoptosis by inhibition of survivin expression." dans: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1838-44, (2004) (PubMed).

Allen, Florell, Hanks, Alexander, Diedrich, Altieri, Grossman: "Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression." dans: Cancer research, Vol. 63, Issue 3, pp. 567-72, (2003) (PubMed).

Détails sur Survivin

Antigène: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Autre désignation: IAP4 / BIRC5 (BIRC5 Produits)

Synonymes: anticorps AP14, anticorps API4, anticorps EPR-1, anticorps AAC-11, anticorps Api4, anticorps TIAP, anticorps survivin40, anticorps bir5a, anticorps survivin, anticorps BIR1, anticorps Su2, anticorps XBIR1, anticorps XSurvivin1, anticorps Xsvv1, anticorps api4, anticorps bir1-A, anticorps epr-1, anticorps svv1, anticorps xSurvivin, anticorps xsurv, anticorps Su1, anticorps birc5.2, anticorps svv2, anticorps xSurvivin2, anticorps bir5b, anticorps SIX, anticorps birc5.2-a, anticorps birc5.2-b, anticorps baculoviral IAP repeat containing 5, anticorps baculoviral IAP repeat-containing 5, anticorps baculoviral IAP repeat containing 5a, anticorps baculoviral IAP repeat-containing 5, gene 1 L homeolog, anticorps baculoviral IAP repeat containing 5 L homeolog, anticorps baculoviral IAP repeat containing 5b, anticorps baculoviral IAP repeat containing 5 S homeolog, anticorps BIRC5, anticorps Birc5, anticorps birc5a, anticorps birc5.1.L, anticorps birc5.2.L, anticorps birc5b, anticorps birc5.2.S

ID gène: 332

Pathways: Apoptose, Cycle Cellulaire, Nuclear Hormone Receptor Binding