IGF2R anticorps

N° du produit ABIN535479

Détail du produit anti-IGF2R anticorps

Antigène: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGF2R est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Fonction: Mouse monoclonal antibody raised against recombinant IGF2R.

Specificité: This antibody recognizes an epitope between domains 2 and 5 of CD222 (IGF2 receptor), a ubiquitously expressed 250 KDa multifunctional type I transmembrane protein.The majority of CD222 is found in the late endosomal/prelysosomal compartment, 5-10 % inthe plasma membrane and the truncated (220 KDa) form of CD222 is present in human and bovine serum.

Réactivité croisée: Humain

Immunogène: Recombinant protein corresponding to human IGF2R.

Clone: MEM-238

Isotype: IgG1

Information d'application

Indications d'application: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS, pH 7.4 (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze.
Avoid repeated freezing and thawing.

Références pour anticorps anti-IGF2R (ABIN535479)

Wood, Hulett: "Cell surface-expressed cation-independent mannose 6-phosphate receptor (CD222) binds enzymatically active heparanase independently of mannose 6-phosphate to promote extracellular matrix degradation." dans: The Journal of biological chemistry, Vol. 283, Issue 7, pp. 4165-76, (2008) (PubMed).

Leksa, Godar, Schiller, Fuertbauer, Muhammad, Slezakova, Horejsi, Steinlein, Weidle, Binder, Stockinger: "TGF-beta-induced apoptosis in endothelial cells mediated by M6P/IGFII-R and mini-plasminogen." dans: Journal of cell science, Vol. 118, Issue Pt 19, pp. 4577-86, (2005) (PubMed).

Gasanov, Koina, Beagley, Aitken, Hansbro: "Identification of the insulin-like growth factor II receptor as a novel receptor for binding and invasion by Listeria monocytogenes." dans: Infection and immunity, Vol. 74, Issue 1, pp. 566-77, (2005) (PubMed).

Détails sur IGF2R

Antigène: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Autre désignation: CD222 / IGF2R (IGF2R Produits)

Synonymes: anticorps CD222, anticorps CIMPR, anticorps M6P-R, anticorps MPR1, anticorps MPRI, anticorps AI661837, anticorps CI-MPR, anticorps M6P/IGF2R, anticorps Mpr300, anticorps mpri, anticorps cd222, anticorps cimpr, anticorps m6p-r, anticorps insulin like growth factor 2 receptor, anticorps insulin-like growth factor 2 receptor, anticorps IGF2R, anticorps Igf2r, anticorps igf2r

ID gène: 3482