CD86 anticorps (APC)

N° du produit ABIN536040

Détail du produit anti-CD86 anticorps (APC)

Antigène: CD86

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD86 est conjugé à/à la APC

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Fonction: Mouse monoclonal antibody raised against native CD86.

Specificité: This antibody reacts with CD86 (B7-2), a 70 KDa type I transmembrane glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.

Réactivité croisée: Humain

Immunogène: Native purified CD86 from human ARH-77 cell.

Clone: BU63

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry (10 µL in human blood cells 100 µL in whole blood or 10⁶ cells in a suspension)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-CD86 (APC) (ABIN536040)

Eri, Kodumudi, Summerlin, Srinivasan: "Suppression of colon inflammation by CD80 blockade: evaluation in two murine models of inflammatory bowel disease." dans: Inflammatory bowel diseases, Vol. 14, Issue 4, pp. 458-70, (2008) (PubMed).

Giguère, Bounou, Paquette, Madrenas, Tremblay: "Insertion of host-derived costimulatory molecules CD80 (B7.1) and CD86 (B7.2) into human immunodeficiency virus type 1 affects the virus life cycle." dans: Journal of virology, Vol. 78, Issue 12, pp. 6222-32, (2004) (PubMed).

Détails sur CD86

Antigène: CD86

Autre désignation: CD86 (CD86 Produits)

Synonymes: anticorps B7-2, anticorps B7.2, anticorps B70, anticorps CD28LG2, anticorps LAB72, anticorps B7, anticorps CLS1, anticorps Cd28l2, anticorps ETC-1, anticorps Ly-58, anticorps Ly58, anticorps MB7, anticorps MB7-2, anticorps TS/A-2, anticorps CD86 molecule, anticorps CD86 antigen, anticorps integrin subunit alpha 2b, anticorps CD86, anticorps Cd86, anticorps Itga2b

ID gène: 942

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation