DcR1 anticorps (AA 1-280) (PE)

N° du produit ABIN536703

Détail du produit anti-DcR1 anticorps (PE)

Antigène: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Épitope: AA 1-280

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DcR1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Fonction: Mouse monoclonal antibody raised against recombinant TNFRSF10C.

Specificité: This antibody reacts with TRAIL-R3, a 35 KDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.

Réactivité croisée: Humain

Immunogène: Recombinant Fc fusion protein corresponding to amino acids 1-280 of TNFRSF10C.

Clone: TRAIL-R3-02

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry (3 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-DcR1 (PE) (ABIN536703)

Mérino, Lalaoui, Morizot, Schneider, Solary, Micheau: "Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2." dans: Molecular and cellular biology, Vol. 26, Issue 19, pp. 7046-55, (2006) (PubMed).

Sanlioglu, Dirice, Aydin, Erin, Koksoy, Sanlioglu: "Surface TRAIL decoy receptor-4 expression is correlated with TRAIL resistance in MCF7 breast cancer cells." dans: BMC cancer, Vol. 5, pp. 54, (2005) (PubMed).

Clancy, Mruk, Archer, Woelfel, Mongkolsapaya, Screaton, Lenardo, Chan: "Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 50, pp. 18099-104, (2005) (PubMed).

Détails sur DcR1

Antigène: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Autre désignation: CD263 / TRAILR3 (TNFRSF10C Produits)

Synonymes: anticorps CD263, anticorps DCR1, anticorps DCR1-TNFR, anticorps LIT, anticorps TRAIL-R3, anticorps TRAILR3, anticorps TRID, anticorps TNFRSF10C, anticorps TNF receptor superfamily member 10c, anticorps TNFRSF10C

ID gène: 8794

Pathways: Apoptose