CDKN1B anticorps (pThr157)

N° du produit ABIN537706

Détail du produit anti-CDKN1B anticorps

Antigène: CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))

Épitope: pThr157

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDKN1B est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of CDKN1B.

Réactivité croisée: Humain

Immunogène: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T157 of human CDKN1B.

Information d'application

Indications d'application: Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-CDKN1B (ABIN537706)

Wingate, Zhang, McGarhen, Bedrosian, Harper, Keyomarsi: "The tumor-specific hyperactive forms of cyclin E are resistant to inhibition by p21 and p27." dans: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 15148-57, (2005) (PubMed).

Kawamata, Inagaki, Mizumura, Sugimoto, Sakajiri, Ohyanagi-Hara, Oshimi: "Methylation status analysis of cell cycle regulatory genes (p16INK4A, p15INK4B, p21Waf1/Cip1, p27Kip1 and p73) in natural killer cell disorders." dans: European journal of haematology, Vol. 74, Issue 5, pp. 424-9, (2005) (PubMed).

Andreu, Lledó, Poch, Ivorra, Albero, Martínez-Climent, Montiel-Duarte, Rifón, Pérez-Calvo, Arbona, Prósper, Pérez-Roger: "BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells." dans: Cancer research, Vol. 65, Issue 8, pp. 3264-72, (2005) (PubMed).

Détails sur CDKN1B

Antigène: CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))

Autre désignation: CDKN1B / KIP1 (CDKN1B Produits)

Synonymes: anticorps CDKN4, anticorps KIP1, anticorps MEN1B, anticorps MEN4, anticorps P27KIP1, anticorps cdkn1b, anticorps sb:cb611, anticorps wu:fb63g10, anticorps wu:fb64g10, anticorps wu:fe18e03, anticorps CDKN1B, anticorps Kip1, anticorps p27, anticorps FAM14D, anticorps ISG12, anticorps ISG12A, anticorps P27, anticorps Cdki1b, anticorps AA408329, anticorps AI843786, anticorps p27Kip1, anticorps cdkn1bl, anticorps cyclin dependent kinase inhibitor 1B, anticorps cyclin-dependent kinase inhibitor 1Bb, anticorps interferon alpha inducible protein 27, anticorps cyclin-dependent kinase inhibitor 1B, anticorps cyclin-dependent kinase inhibitor 1Ba, anticorps CDKN1B, anticorps cdkn1bb, anticorps IFI27, anticorps Cdkn1b, anticorps cdkn1ba

ID gène: 1027

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy