MARK2 anticorps (pThr595)

N° du produit ABIN538475

Détail du produit anti-MARK2 anticorps

Antigène: MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

Épitope: pThr595

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARK2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of MARK2.

Specificité: Reactivity occurs against human MARK2 pT595 protein and This antibody is specific to the phosphorylated form of the protein. Reactivity with non-phosphorylated human MARK2 is minimal by ELISA. Expect at least partial reactivity with other isoforms of MARK. The immunogen sequence is present in all forms identified to date and localizes to T595 on MARK2, T587 on MARK3, T591 on MARK1 and T568 on MARK4.

Réactivité croisée: Boeuf (Vache), Chien, Humain, Souris, Rat

Attributs du produit: Antibody Reactive Against Synthetic Peptide.

Immunogène: Synthetic phosphopeptide corresponding to residues surrounding T595 of human MARK2.

Information d'application

Indications d'application: ELISA (1:1000-1:3000)
Western Blot (1:250-1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-MARK2 (ABIN538475)

Hurov, Watkins, Piwnica-Worms: "Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity." dans: Current biology : CB, Vol. 14, Issue 8, pp. 736-41, (2004) (PubMed).

Hueso, Beltran, Moreso, Ciriero, Fulladosa, Grinyó, Serón, Navarro et al.: "Splicing alterations in human renal allografts: detection of a new splice variant of protein kinase Par1/Emk1 whose expression is associated with an increase of inflammation in protocol biopsies of ..." dans: Biochimica et biophysica acta, Vol. 1689, Issue 1, pp. 58-65, (2004) (PubMed).

Sun, Lu, Feng, Reinhard, Jan, Fantl, Williams: "PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling." dans: Nature cell biology, Vol. 3, Issue 7, pp. 628-36, (2001) (PubMed).

Détails sur MARK2

Antigène: MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

Autre désignation: MARK2 (MARK2 Produits)

Synonymes: anticorps EMK-1, anticorps EMK1, anticorps PAR-1, anticorps Par-1b, anticorps Par1b, anticorps AU024026, anticorps Emk, anticorps Par-1, anticorps mKIAA4207, anticorps microtubule affinity regulating kinase 2, anticorps MAP/microtubule affinity regulating kinase 2, anticorps MARK2, anticorps Mark2

ID gène: 2011

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2