FANCD2 anticorps (N-Term)

N° du produit ABIN540721

Détail du produit anti-FANCD2 anticorps

Antigène: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCD2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Fonction: Rabbit polyclonal antibody raised against partial recombinant FANCD2.

Specificité: This antibody is specific to FANCD2.

Réactivité croisée: Humain, Souris

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: Recombinant protein corresponding to N-terminus of human FANCD2.

Information d'application

Indications d'application: Immunofluorescence (1:200-1:500)
Western Blot (1:10000-1:20000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5-5 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In Tris-glycine, 150 mM NaCl (0.05 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-FANCD2 (ABIN540721)

Bekker-Jensen, Lukas, Kitagawa, Melander, Kastan, Bartek, Lukas: "Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks." dans: The Journal of cell biology, Vol. 173, Issue 2, pp. 195-206, (2006) (PubMed).

Tremblay, Pintor Dos Reis, Bradley, Galloni, Perez-Ordonez, Freeman, Brown, Gilbert, Gullane, Irish, Kamel-Reid: "Young patients with oral squamous cell carcinoma: study of the involvement of GSTP1 and deregulation of the Fanconi anemia genes." dans: Archives of otolaryngology--head & neck surgery, Vol. 132, Issue 9, pp. 958-66, (2006) (PubMed).

Mukhopadhyay, Leung, Hicks, Hastings, Youssoufian, Plon: "Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia." dans: The Journal of cell biology, Vol. 175, Issue 2, pp. 225-35, (2006) (PubMed).

Stiff, Reis, Alderton, Woodbine, ODriscoll, Jeggo: "Nbs1 is required for ATR-dependent phosphorylation events." dans: The EMBO journal, Vol. 24, Issue 1, pp. 199-208, (2005) (PubMed).

Rothfuss, Grompe: "Repair kinetics of genomic interstrand DNA cross-links: evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway." dans: Molecular and cellular biology, Vol. 24, Issue 1, pp. 123-34, (2003) (PubMed).

Détails sur FANCD2

Antigène: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Autre désignation: FANCD2 (FANCD2 Produits)

Synonymes: anticorps FANCD2, anticorps CG17269, anticorps CG31192, anticorps CG31194, anticorps Dmel\\CG17269, anticorps dmFANCD2, anticorps xfancd2, anticorps FA-D2, anticorps FA4, anticorps FACD, anticorps FAD, anticorps FAD2, anticorps FANCD, anticorps 2410150O07Rik, anticorps AU015151, anticorps BB137857, anticorps Fanconi anemia complementation group D2, anticorps CG17269 gene product from transcript CG17269-RA, anticorps Fanconi anemia group D2 protein, anticorps Fanconi anemia, complementation group D2, anticorps Fanconi anemia complementation group D2 L homeolog, anticorps FANCD2, anticorps Fancd2, anticorps LOC100455970, anticorps fancd2, anticorps fancd2.L

ID gène: 2177

Pathways: Réparation de l'ADN