ATG5 anticorps (AA 1-50)

N° du produit ABIN540779

Détail du produit anti-ATG5 anticorps

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Épitope: AA 1-50

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Porc, Xenopus laevis, Primate

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of ATG5.

Specificité: This antibody is selective for the full-length and calpain cleaved isoform proteins. The short isoform is missing a.a. 1-79. The calpain cleaved form of ATG5 is missing a.a. 195-275.

Réactivité croisée: Boeuf (Vache), Humain, Souris, Porc, Primate, Rat, Xenopus laevis, Poisson zèbre (Danio rerio)

Immunogène: A synthetic peptide corresponding to amino acids 1-50 of human ATG5.

Information d'application

Indications d'application: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5 μg/mL)
Western Blot (1:500)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (30 % glycerol, 0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-ATG5 (ABIN540779)

Wang, Singh, Massey, Kane, Kaushik, Grant, Xiang, Cuervo, Czaja: "Loss of macroautophagy promotes or prevents fibroblast apoptosis depending on the death stimulus." dans: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4766-77, (2008) (PubMed).

Pyo, Nah, Kim, Lee, Heo, Lee, Jung: "Compensatory activation of ERK1/2 in Atg5-deficient mouse embryo fibroblasts suppresses oxidative stress-induced cell death." dans: Autophagy, Vol. 4, Issue 3, pp. 315-21, (2008) (PubMed).

Cadwell, Liu, Brown, Miyoshi, Loh, Lennerz, Kishi, Kc, Carrero, Hunt, Stone, Brunt, Xavier, Sleckman, Li, Mizushima, Stappenbeck, Virgin: "A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells." dans: Nature, Vol. 456, Issue 7219, pp. 259-63, (2008) (PubMed).

Détails sur ATG5

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Autre désignation: APG5L / ATG5 (ATG5 Produits)

Synonymes: anticorps APG5, anticorps APG5-LIKE, anticorps APG5L, anticorps ASP, anticorps hAPG5, anticorps ATG5, anticorps CG1643, anticorps DmAtg5, anticorps Dmel\\CG1643, anticorps atg5, anticorps 2010107M05Rik, anticorps 3110067M24Rik, anticorps AW319544, anticorps Apg5l, anticorps Atg5l, anticorps C88337, anticorps Paddy, anticorps apg5l, anticorps zgc:100934, anticorps ATATG5, anticorps AUTOPHAGY 5, anticorps MKP11.20, anticorps MKP11_20, anticorps autophagy related 5, anticorps Autophagy-related 5, anticorps ATG5 autophagy related 5 homolog (S. cerevisiae), anticorps autophagy related 5 L homeolog, anticorps similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12, anticorps autophagy protein Apg5 family, anticorps ATG5, anticorps Atg5, anticorps atg5, anticorps atg5.L, anticorps APG5

ID gène: 9474

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy