SMAD4 anticorps (Thr277)

N° du produit ABIN542927

Détail du produit anti-SMAD4 anticorps

Antigène: SMAD4 (SMAD Family Member 4 (SMAD4))

Épitope: Thr277

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD4 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of SMAD4.

Réactivité croisée: Humain

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding T277 of human SMAD4.

Information d'application

Indications d'application: Dot Blot (1:500)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-SMAD4 (ABIN542927)

Zhang, Lui: "Transforming growth factor-?3 regulates cell junction restructuring via MAPK-mediated mRNA destabilization and Smad-dependent protein degradation of junctional adhesion molecule B (JAM-B)." dans: Biochimica et biophysica acta, Vol. 1849, Issue 6, pp. 601-11, (2015) (PubMed).

Xiao, Ho, Liong, Nanji, Leung, Lau, Fung, Tipoe: "Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways." dans: European journal of nutrition, Vol. 53, Issue 1, pp. 187-99, (2014) (PubMed).

Xiao, Xing, Huo, Fung, Liong, Ching, Xu, Chang, So, Tipoe: "Lycium barbarum polysaccharides therapeutically improve hepatic functions in non-alcoholic steatohepatitis rats and cellular steatosis model." dans: Scientific reports, Vol. 4, pp. 5587, (2014) (PubMed).

Wang, Lui: "Transforming growth factor-?1 attenuates junctional adhesion molecule-A and contributes to breast cancer cell invasion." dans: European journal of cancer (Oxford, England : 1990), Vol. 48, Issue 18, pp. 3475-87, (2012) (PubMed).

Horvath, Henshall, Kench, Turner, Golovsky, Brenner, ONeill, Kooner, Stricker, Grygiel, Sutherland: "Loss of BMP2, Smad8, and Smad4 expression in prostate cancer progression." dans: The Prostate, Vol. 59, Issue 3, pp. 234-42, (2004) (PubMed).

Sekiya, Oda, Matsuura, Akiyama: "Transcriptional regulation of the TGF-beta pseudoreceptor BAMBI by TGF-beta signaling." dans: Biochemical and biophysical research communications, Vol. 320, Issue 3, pp. 680-4, (2004) (PubMed).

Li, Xin, Xu, Huang, Zhang, Chen, Zhang, Fu, Chang: "CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription." dans: Molecular and cellular biology, Vol. 24, Issue 2, pp. 856-64, (2003) (PubMed).

Détails sur SMAD4

Antigène: SMAD4 (SMAD Family Member 4 (SMAD4))

Autre désignation: SMAD4 (SMAD4 Produits)

Synonymes: anticorps smad4, anticorps DPC4, anticorps JIP, anticorps MADH4, anticorps MYHRS, anticorps AW743858, anticorps D18Wsu70e, anticorps Madh4, anticorps XSmad4alpha, anticorps Xsmad4, anticorps dpc4, anticorps jip, anticorps madh4, anticorps xsmad4a, anticorps SMAD family member 4, anticorps Smad4 protein, anticorps SMAD family member 4, gene 1 L homeolog, anticorps SMAD4, anticorps smad4, anticorps Smad4, anticorps smad4.1.L

ID gène: 4089

Pathways: Cycle Cellulaire, Chromatin Binding, Autophagy