SIGMAR1
Reactivité: Humain
ELISA
Hôte: Lapin
Polyclonal
Biotin
Indications d'application
Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (0.09 % sodium azide)
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Lee, Chen, Schetz et al.: "An unambiguous assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and a distinct structure-affinity relationship for ..." dans: European journal of pharmacology, Vol. 578, Issue 2-3, pp. 123-36, (2008) (PubMed).
Cobos, del Pozo, Baeyens: "Irreversible blockade of sigma-1 receptors by haloperidol and its metabolites in guinea pig brain and SH-SY5Y human neuroblastoma cells." dans: Journal of neurochemistry, Vol. 102, Issue 3, pp. 812-25, (2007) (PubMed).
Maurice, Grégoire, Espallergues: "Neuro(active)steroids actions at the neuromodulatory sigma1 (sigma1) receptor: biochemical and physiological evidences, consequences in neuroprotection." dans: Pharmacology, biochemistry, and behavior, Vol. 84, Issue 4, pp. 581-97, (2006) (PubMed).