BTK anticorps (AA 209-239)

N° du produit ABIN544377

Détail du produit anti-BTK anticorps

Antigène: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Épitope: AA 209-239

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BTK est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of BTK.

Réactivité croisée: Humain

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to amino acids 209-239 at internal region of human BTK.

Information d'application

Indications d'application: Immunofluorescence (1:10-50)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 2 weeks. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-BTK (ABIN544377)

Márquez, Smith, Petoukhov, Lo Surdo, Mattsson, Knekt, Westlund, Scheffzek, Saraste, Svergun: "Conformation of full-length Bruton tyrosine kinase (Btk) from synchrotron X-ray solution scattering." dans: The EMBO journal, Vol. 22, Issue 18, pp. 4616-24, (2003) (PubMed).

Jefferies, Doyle, Brunner, Dunne, Brint, Wietek, Walch, Wirth, ONeill: "Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4." dans: The Journal of biological chemistry, Vol. 278, Issue 28, pp. 26258-64, (2003) (PubMed).

Horwood, Mahon, McDaid, Campbell, Mano, Brennan, Webster, Foxwell: "Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production." dans: The Journal of experimental medicine, Vol. 197, Issue 12, pp. 1603-11, (2003) (PubMed).

Détails sur BTK

Antigène: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Autre désignation: BTK (BTK Produits)

Synonymes: anticorps BTK, anticorps atk, anticorps bpk, anticorps xla, anticorps imd1, anticorps agmx1, anticorps psctk1, anticorps AGMX1, anticorps AT, anticorps ATK, anticorps BPK, anticorps IMD1, anticorps PSCTK1, anticorps XLA, anticorps AI528679, anticorps xid, anticorps Bruton tyrosine kinase, anticorps Bruton agammaglobulinemia tyrosine kinase, anticorps BTK, anticorps btk, anticorps Btk

ID gène: 695

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling