APP anticorps (C-Term)

N° du produit ABIN545823

Détail du produit anti-APP anticorps

Antigène: APP (Amyloid beta (A4) Precursor Protein (APP))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APP est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of APP.

Réactivité croisée: Humain

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human APP.

Information d'application

Indications d'application: ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-APP (ABIN545823)

Lleó, Berezovska, Ramdya, Fukumoto, Raju, Shah, Hyman: "Notch1 competes with the amyloid precursor protein for gamma-secretase and down-regulates presenilin-1 gene expression." dans: The Journal of biological chemistry, Vol. 278, Issue 48, pp. 47370-5, (2003) (PubMed).

Zhou, Su, Li, Liu, Ryder, Wu, Gonzalez-DeWhitt, Gelfanova, Hale, May, Paul, Ni: "Nonsteroidal anti-inflammatory drugs can lower amyloidogenic Abeta42 by inhibiting Rho." dans: Science (New York, N.Y.), Vol. 302, Issue 5648, pp. 1215-7, (2003) (PubMed).

Borroni, Colciaghi, Caltagirone, Rozzini, Broglio, Cattabeni, Di Luca, Padovani: "Platelet amyloid precursor protein abnormalities in mild cognitive impairment predict conversion to dementia of Alzheimer type: a 2-year follow-up study." dans: Archives of neurology, Vol. 60, Issue 12, pp. 1740-4, (2003) (PubMed).

Détails sur APP

Antigène: APP (Amyloid beta (A4) Precursor Protein (APP))

Autre désignation: Amyloid beta A4 protein / APP (APP Produits)

Synonymes: anticorps AAA, anticorps ABETA, anticorps ABPP, anticorps AD1, anticorps APPI, anticorps CTFgamma, anticorps CVAP, anticorps PN-II, anticorps PN2, anticorps aaa, anticorps abeta, anticorps abpp, anticorps ad1, anticorps appi, anticorps ctfgamma, anticorps cvap, anticorps pn2, anticorps APP, anticorps APP-like, anticorps APPL, anticorps Abeta, anticorps BcDNA:GH04413, anticorps CG7727, anticorps Dmel\\CG7727, anticorps EG:65F1.5, anticorps appl, anticorps Abpp, anticorps Adap, anticorps Ag, anticorps Cvap, anticorps E030013M08Rik, anticorps betaApp, anticorps app, anticorps wu:fj34d10, anticorps wu:fk65e12, anticorps zgc:85740, anticorps amyloid beta precursor protein, anticorps amyloid beta (A4) precursor protein, anticorps beta amyloid protein precursor-like, anticorps amyloid beta (A4) precursor protein a, anticorps amyloid beta precursor protein L homeolog, anticorps APP, anticorps app, anticorps Appl, anticorps App, anticorps appa, anticorps app.L

ID gène: 351

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour