AFT7 anticorps (Middle Region)

N° du produit ABIN5514514

Détail du produit anti-AFT7 anticorps

Antigène: AFT7 (Activating Transcription Factor 7 (AFT7))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AFT7 est non-conjugé

Application: Western Blotting (WB)

Séquence: GYDPLHPTLP SPTSVITQAP PSNRQMGSPT GSLPLVMHLA NGQTMPVLPG

Attributs du produit: This is a rabbit polyclonal antibody against ATF7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human ATF7

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AFT7

Antigène: AFT7 (Activating Transcription Factor 7 (AFT7))

Autre désignation: ATF7 (AFT7 Produits)

Synonymes: anticorps ATFA, anticorps 1110012F10Rik, anticorps 9430065F09Rik, anticorps AI549878, anticorps C130020M04Rik, anticorps ATF7, anticorps fa97a09, anticorps fc25b12, anticorps wu:fa97a09, anticorps wu:fc25b12, anticorps atfa, anticorps activating transcription factor 7, anticorps activating transcription factor 7b, anticorps ATF7, anticorps Atf7, anticorps atf7b, anticorps atf7

Sujet: Isoform 5/ATF-4 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation. FUNCTION: Isoform 4/ATF-A0 acts as a dominant repressor of the E- selectin/NF-ELAM1/delta-A promoter.ATF7 Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]- 3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.

Alias Symbols: ATF7, ATFA,

Protein Interaction Partner: FCER2, TMEM239, FAM9B, CCDC155, MITD1, OCIAD1, TAOK3, URI1, MAPK8, UBC, CREB1, Cebpb, SUMO2, YY1, BCL6, TAF12, TAF4, MAPK9, PTP4A1, PTP4A2, FOS, ATF2, JDP2,

Protein Size: 473

ID gène: 11016