Bestrophin 1 anticorps (Middle Region)

N° du produit ABIN5514576

Détail du produit anti-Bestrophin 1 anticorps

Antigène: Bestrophin 1 (BEST1)

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Bestrophin 1 est non-conjugé

Application: Western Blotting (WB)

Séquence: KAYPGHELDL VVPVFTFLQF FFYVGWLKVA EQLINPFGED DDDFETNWIV

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human BEST1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Bestrophin 1

Antigène: Bestrophin 1 (BEST1)

Autre désignation: BEST1 (BEST1 Produits)

Synonymes: anticorps CG6264, anticorps Dbest, anticorps Dmel\\CG6264, anticorps anon-WO0118547.380, anticorps best, anticorps dBest1, anticorps dbest1, anticorps dmBest1, anticorps BEST1, anticorps VMD2, anticorps best-1, anticorps ARB, anticorps BEST, anticorps BMD, anticorps RP50, anticorps TU15B, anticorps Bmd, anticorps Vmd2, anticorps mBest1, anticorps Bestrophin 1, anticorps bestrophin 1, anticorps Best1, anticorps BEST1, anticorps best1, anticorps Bm1_25500

Sujet: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

Alias Symbols: ARB, BMD, BEST, RP50, VMD2, TU15B

Protein Size: 498

ID gène: 7439

NCBI Accession: NM_001139443, NP_001132915