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Bestrophin 1 anticorps

BEST1 Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7260777
  • Antigène Voir toutes Bestrophin 1 (BEST1) Anticorps
    Bestrophin 1 (BEST1)
    Reactivité
    • 25
    • 4
    • 3
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 21
    • 4
    Lapin
    Clonalité
    • 23
    • 2
    Polyclonal
    Conjugué
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Bestrophin 1 est non-conjugé
    Application
    • 16
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    A synthetic peptide of human BEST1 (NP_004174.1).
    Isotype
    IgG
  • Indications d'application
    WB 1:500-1:2000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    Bestrophin 1 (BEST1)
    Autre désignation
    BEST1 (BEST1 Produits)
    Synonymes
    anticorps CG6264, anticorps Dbest, anticorps Dmel\\CG6264, anticorps anon-WO0118547.380, anticorps best, anticorps dBest1, anticorps dbest1, anticorps dmBest1, anticorps BEST1, anticorps VMD2, anticorps best-1, anticorps ARB, anticorps BEST, anticorps BMD, anticorps RP50, anticorps TU15B, anticorps Bmd, anticorps Vmd2, anticorps mBest1, anticorps Bestrophin 1, anticorps bestrophin 1, anticorps Best1, anticorps BEST1, anticorps best1, anticorps Bm1_25500
    Sujet
    This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
    Poids moléculaire

    Observed_MW: 70 kDa

    Calculated_MW: 57 kDa/67 kDa/69 kDa

    ID gène
    7439
    UniProt
    O76090
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