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CARD11 anticorps (Middle Region)
CARD11
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5514600
Détail du produit anti-CARD11 anticorps
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Antigène
Voir toutes CARD11 Anticorps
CARD11
(Caspase Recruitment Domain Family, Member 11 (CARD11))
Épitope
Tous les épitopes à travers CARD11 Anticorps.
Middle Region
Reactivité
Toutes les réactivités sur CARD11 Anticorps
Humain
Hôte
Toutes les hôtes sur CARD11 Anticorps
Lapin
Clonalité
Toutes les clonalités sur CARD11 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CARD11 Anticorps
Cet anticorp CARD11 est non-conjugé
Application
Tous les applications à travers CARD11 Anticorps.
Western Blotting (WB)
Séquence
SPRLSRASFL FGQLLQFVSR SENKYKRMNS NERVRIISGS PLGSLARSSL
Purification
Affinity purified
Immunogène
The immunogen is a synthetic peptide directed towards the middle region of human CARD11
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur CARD11
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Antigène
CARD11
(Caspase Recruitment Domain Family, Member 11 (CARD11))
Autre désignation
CARD11 (CARD11 Produits )
Synonymes
anticorps BENTA, anticorps BIMP3, anticorps CARMA1, anticorps PPBL, anticorps 0610008L17Rik, anticorps 2410011D02Rik, anticorps CARD11, anticorps LOC100232755, anticorps caspase recruitment domain family member 11, anticorps caspase recruitment domain family, member 11, anticorps caspase recruitment domain-containing protein 11, anticorps CARD11, anticorps Card11, anticorps LOC100550812, anticorps card11
Sujet
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Alias Symbols: PPBL, BENTA, BIMP3, IMD11, CARMA1 Protein Size: 1171
ID gène
84433
NCBI Accession
NM_032415 , NP_115791
UniProt
Q8TES3
Pathways
TCR Signaling , Fc-epsilon Receptor Signaling Pathway , BCR Signaling
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