CRADD anticorps (Middle Region)

N° du produit ABIN5514604

Détail du produit anti-CRADD anticorps

Antigène: CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRADD est non-conjugé

Application: Western Blotting (WB)

Séquence: PAGDRLTGIP SHILNSSPSD RQINQLAQRL GPEWEPMVLS LGLSQTDIYR

Attributs du produit: This is a rabbit polyclonal antibody against CRADD. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human CRADD

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CRADD

Antigène: CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))

Autre désignation: CRADD (CRADD Produits)

Synonymes: anticorps cradd, anticorps MGC89035, anticorps zgc:101717, anticorps CRADD, anticorps DKFZp468A2219, anticorps LOC100226369, anticorps raidd, anticorps MGC78788, anticorps MRT34, anticorps RAIDD, anticorps CASP2 and RIPK1 domain containing adaptor with death domain, anticorps CASP2 and RIPK1 domain containing adaptor with death, gene 1, anticorps CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog, anticorps CRADD, anticorps cradd.1, anticorps cradd, anticorps cradd.2.S, anticorps Cradd

Sujet: The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.

Alias Symbols: CRADD, RAIDD,

Protein Interaction Partner: BBS5, TRIM54, APPL2, KCTD9, CASP2, PIDD1, CRYAB, DCXR, SLC35A3, VTN, KPNA1, IL9R, APP, MYC, LRIF1, CCSER2, C14orf1, RIPK1, CASP8, EEF1A1, TNFRSF1A, ced-3,

Protein Size: 199

ID gène: 8738

NCBI Accession: NP_003796

UniProt: P78560

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity