COL18A1 anticorps (Middle Region)

N° du produit ABIN5514687

Détail du produit anti-COL18A1 anticorps

Antigène: COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))

Épitope: Middle Region

Reactivité: Humain, Boeuf (Vache), Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL18A1 est non-conjugé

Application: Western Blotting (WB)

Séquence: VQLEARTPLP RGTDNEVAAL QPPVVQLHDS NPYPRREHPH PTARPWRADD

Homologie: Cow: 92%, Horse: 83%, Human: 100%, Pig: 83%, Rabbit: 100%

Attributs du produit: This is a rabbit polyclonal antibody against COIA1. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen for Anti-COL18A1 antibody is: synthetic peptide directed towards the Middle region of Human COIA1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur COL18A1

Antigène: COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))

Autre désignation: COL18A1 (COL18A1 Produits)

Synonymes: anticorps KNO, anticorps KNO1, anticorps KS, anticorps cb371, anticorps cb529, anticorps fc96d06, anticorps sb:cb529, anticorps wu:fb47h10, anticorps wu:fb77g12, anticorps wu:fc50f04, anticorps wu:fc96d06, anticorps wu:fk02h12, anticorps kno, anticorps kno1, anticorps collagen type XVIII alpha 1 chain, anticorps collagen type XVIII alpha 1 chain a, anticorps collagen, type XVIII, alpha 1, anticorps collagen type XVIII alpha 1, anticorps COL18A1, anticorps col18a1a, anticorps Col18a1, anticorps col18a1

Sujet: This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants.

Alias Symbols: KS, KNO, KNO1

Protein Interaction Partner: FUS, TUBG1, FBXO6, HNRNPD, TECPR1, GPC1, GPC4, KDR, FBLN2, ITGA5, MMP2, CTSL,

Protein Size: 1339

ID gène: 80781