IL1RAP anticorps (C-Term)

N° du produit ABIN5514899

Détail du produit anti-IL1RAP anticorps

Antigène: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL1RAP est non-conjugé

Application: Western Blotting (WB)

Séquence: LVQYKAVKET KVKELKRAKT VLTVIKWKGE KSKYPQGRFW KQLQVAMPVK

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human IL1RAP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IL1RAP

Antigène: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Autre désignation: IL1RAP (IL1RAP Produits)

Synonymes: anticorps IL1RAP, anticorps il-1racp, anticorps il-racp, anticorps il1r3, anticorps C3orf13, anticorps IL-1RAcP, anticorps IL1R3, anticorps 6430709H04Rik, anticorps AI255955, anticorps AV239853, anticorps IL-1RAcp, anticorps Il1racpb, anticorps interleukin 1 receptor accessory protein, anticorps IL1RAP, anticorps il1rap, anticorps il-1racp, anticorps Il1rap

Sujet: Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.

Alias Symbols: IL1R3, C3orf13, IL-1RAcP

Protein Size: 570

ID gène: 3556

NCBI Accession: NM_001167928, NP_001161400

UniProt: Q9NPH3

Pathways: Signalisation NF-kappaB, Growth Factor Binding