PKLR anticorps (N-Term)

N° du produit ABIN5515040

Détail du produit anti-PKLR anticorps

Antigène: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKLR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: TVDPAFRTRG NANTVWVDYP NIVRVVPVGG RIYIDDGLIS LVVQKIGPEG

Attributs du produit: This is a rabbit polyclonal antibody against PKLR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PKLR

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PKLR

Antigène: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Autre désignation: PKLR (PKLR Produits)

Synonymes: anticorps PK1, anticorps PKL, anticorps PKR, anticorps PKRL, anticorps RPK, anticorps Pklg, anticorps wu:fd15e01, anticorps wu:fi37e08, anticorps pk1, anticorps PKLR, anticorps Pk-1, anticorps Pk1, anticorps R-PK, anticorps pklr, anticorps pyruvate kinase L/R, anticorps pyruvate kinase, liver and RBC, anticorps pyruvate kinase, liver and RBC L homeolog, anticorps pyruvate kinase liver and red blood cell, anticorps pyruvate kinase PKLR-like, anticorps PKLR, anticorps Pklr, anticorps pklr, anticorps pklr.L, anticorps LOC100621940

Sujet: The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: PKLR, PK1, PKL,

Protein Interaction Partner: UBC, WWOX, SUMO4, CLEC4G, PCNA, OTUD5, USPL1, USP3, MYOC, KIF23, ARHGEF6, PXN, PAK1,

Protein Size: 574

ID gène: 5313

UniProt: P30613

Pathways: Ribonucleoside Biosynthetic Process