SP100 anticorps (Middle Region)

N° du produit ABIN5515158

Détail du produit anti-SP100 anticorps

Antigène: SP100 (SP100 Nuclear Antigen (SP100))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SP100 est non-conjugé

Application: Western Blotting (WB)

Séquence: IIVISSEDSE GSTDVDEPLE VFISAPRSEP VINNDNPLES NDEKEGQEAT

Attributs du produit: This is a rabbit polyclonal antibody against SP100. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human SP100

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SP100

Antigène: SP100 (SP100 Nuclear Antigen (SP100))

Autre désignation: SP100 (SP100 Produits)

Synonymes: anticorps SP100, anticorps A430075G10Rik, anticorps lysp100b, anticorps SP140, anticorps SP100 nuclear antigen, anticorps nuclear antigen Sp100, anticorps nuclear autoantigen Sp-100, anticorps SP100, anticorps Sp100, anticorps LOC101120993

Sujet: This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene, one of which encodes a high-mobility group protein.

Alias Symbols: SP100,

Protein Interaction Partner: RBM39, DYRK2, SUMO1, UBE2I, SP100, SUMO2, SUMO3, PHC1, DNMT3A, ACTN2, RTP5, L3MBTL3, TRAF3IP3, GIPC2, AMOTL2, ZC2HC1A, SENP1, CBX5, USPL1, UBC, PML, VPS25, PUS1, CRTAP, TOM1L1, SERPINE2, AGL, CREM, DSTN, AHCYL1, SEC23A, IGBP1, ETS1, ARID3A, TERF2IP, TERF2

Protein Size: 879

ID gène: 6672

NCBI Accession: NP_003104

UniProt: P23497

Pathways: Retinoic Acid Receptor Signaling Pathway