Translin anticorps (Middle Region)

N° du produit ABIN5515344

Détail du produit anti-Translin anticorps

Antigène: Translin (TSN)

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Translin est non-conjugé

Application: Western Blotting (WB)

Séquence: VNSVTAGDYS RPLHISTFIN ELDSGFRLLN LKNDSLRKRY DGLKYDVKKV

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TSN

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Translin

Antigène: Translin (TSN)

Autre désignation: TSN (TSN Produits)

Synonymes: anticorps tsn, anticorps MGC52533, anticorps TSN, anticorps CG11761, anticorps Dmel\\CG11761, anticorps TB-RBP, anticorps BCLF-1, anticorps C3PO, anticorps RCHF1, anticorps REHF-1, anticorps TBRBP, anticorps TRSLN, anticorps 2610034C24Rik, anticorps AU040286, anticorps translin L homeolog, anticorps translin, anticorps haloacid dehalogenase, anticorps Translin, anticorps tsn.L, anticorps TSN, anticorps trsn, anticorps MMAH_RS03470, anticorps TAGG_RS05275, anticorps Igag_0962, anticorps MFER_RS03645, anticorps DESMU_RS01315, anticorps ARCVE_RS05265, anticorps MZHIL_RS01310, anticorps Tsn

Sujet: This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants.

Alias Symbols: C3PO, RCHF1, TBRBP, TRSLN, BCLF-1, REHF-1

Protein Size: 228

ID gène: 7247

NCBI Accession: NM_001261401, NP_001248330

UniProt: Q15631