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MECP2 anticorps (N-Term)
MECP2
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5515594
Détail du produit anti-MECP2 anticorps
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Antigène
Voir toutes MECP2 Anticorps
MECP2
(Methyl CpG Binding Protein 2 (MECP2))
Épitope
Tous les épitopes à travers MECP2 Anticorps.
N-Term
Reactivité
Toutes les réactivités sur MECP2 Anticorps
Humain
Hôte
Toutes les hôtes sur MECP2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur MECP2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers MECP2 Anticorps
Cet anticorp MECP2 est non-conjugé
Application
Tous les applications à travers MECP2 Anticorps.
Western Blotting (WB)
Séquence
LDPNDFDFTV TGRGSPSRRE QKPPKKPKSP KAPGTGRGRG RPKGSGTTRP
Attributs du produit
This is a rabbit polyclonal antibody against MECP2. It was validated on Western Blot.
Purification
Affinity purified
Immunogène
The immunogen is a synthetic peptide directed towards the N-terminal region of Human MECP2
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur MECP2
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Antigène
MECP2
(Methyl CpG Binding Protein 2 (MECP2))
Autre désignation
MECP2 (MECP2 Produits )
Synonymes
anticorps AUTSX3, anticorps MRX16, anticorps MRX79, anticorps MRXS13, anticorps MRXSL, anticorps PPMX, anticorps RS, anticorps RTS, anticorps RTT, anticorps 1500041B07Rik, anticorps BB130002, anticorps D630021H01Rik, anticorps Mbd5, anticorps WBP10, anticorps wu:fk96a04, anticorps zgc:111857, anticorps methyl-CpG binding protein 2, anticorps methyl CpG binding protein 2, anticorps methyl-CpG binding protein 2 S homeolog, anticorps MECP2, anticorps Mecp2, anticorps mecp2, anticorps mecp2.S
Sujet
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Protein Size: 486
ID gène
4204
NCBI Accession
XP_005274738
UniProt
P51608
Pathways
Inositol Metabolic Process , Chromatin Binding , Synaptic Membrane
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