Importin 5 anticorps (N-Term)
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- Antigène Voir toutes Importin 5 (IPO5) Anticorps
- Importin 5 (IPO5)
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Importin 5 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- EDEDWANADE LEDDDFDSNA VAGESALDRM ACGLGGKLVL PMIKEHIMQM
- Attributs du produit
- This is a rabbit polyclonal antibody against IPO5. It was validated on Western Blot.
- Purification
- Affinity purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human IPO5
- Top Product
- Discover our top product IPO5 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Importin 5 (IPO5)
- Autre désignation
- IPO5 (IPO5 Produits)
- Synonymes
- anticorps IPO5, anticorps RANBP5, anticorps IMB3, anticorps KPNB3, anticorps Pse1, anticorps imp5, anticorps 1110011C18Rik, anticorps 5730478E03Rik, anticorps AA409333, anticorps C76941, anticorps Kpnb3, anticorps Ranbp5, anticorps importin 5, anticorps IPO5, anticorps Ipo5
- Sujet
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Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
Alias Symbols: IPO5, KPNB3, RANBP5,
Protein Interaction Partner: HUWE1, UBC, STAU1, ASB15, HK2, HEXB, ATIC, MCTS1, TNFAIP8, EZR, UBA1, TXNRD1, FBXO6, BHLHB9, EGFR, MUC1, SOX2, NPM1, HDAC2, LAS1L, PELP1, WASL, VCAM1, MAP1LC3A, ITGA4, FN1, CFTR, RPL7, CA9, NOTCH1, IPO4, TNPO1, KPNB1, RAN, CUL3, ACD, TINF2, TERF1, BKRF1,
Protein Size: 1097 - ID gène
- 3843
- UniProt
- O00410
- Pathways
- Protein targeting to Nucleus
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