CYP7A1 anticorps (Middle Region)

N° du produit ABIN5515922

Détail du produit anti-CYP7A1 anticorps

Antigène: CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP7A1 est non-conjugé

Application: Western Blotting (WB)

Séquence: DPEIYPDPLT FKYDRYLDEN GKTKTTFYCN GLKLKYYYMP FGSGATICPG

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CYP7A1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CYP7A1

Antigène: CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))

Autre désignation: CYP7A1 (CYP7A1 Produits)

Synonymes: anticorps CP7A, anticorps CYP7, anticorps CYPVII, anticorps CHAP, anticorps CYP7S1, anticorps cyp7a1a, anticorps zgc:63920, anticorps cytochrome P450 family 7 subfamily A member 1, anticorps cytochrome P450, family 7, subfamily a, polypeptide 1, anticorps cytochrome P450, family 7, subfamily A, polypeptide 1, anticorps cholesterol 7-alpha-hydroxylase, anticorps CYP7A1, anticorps Cyp7a1, anticorps cyp7a1

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis.

Alias Symbols: CP7A, CYP7, CYPVII

Protein Size: 504

ID gène: 1581

NCBI Accession: NM_000780, NP_000771

UniProt: P22680

Pathways: Steroid Hormone Biosynthesis, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha