DERL1 anticorps (C-Term)

N° du produit ABIN5515996

Détail du produit anti-DERL1 anticorps

Antigène: DERL1 (Der1-Like Domain Family, Member 1 (DERL1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DERL1 est non-conjugé

Application: Western Blotting (WB)

Séquence: STPQFLYRWL PSRRGGVSGF GVPPASMRRA ADQNGGGGRH NWGQGFRLGD

Attributs du produit: This is a rabbit polyclonal antibody against DERL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DERL1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DERL1

Antigène: DERL1 (Der1-Like Domain Family, Member 1 (DERL1))

Autre désignation: DERL1 (DERL1 Produits)

Synonymes: anticorps CG10908, anticorps Dmel\\CG10908, anticorps DDBDRAFT_0188135, anticorps DDBDRAFT_0266772, anticorps DDB_0188135, anticorps DDB_0266772, anticorps MGC84200, anticorps wu:fb09d07, anticorps wu:fb94d05, anticorps wu:fj92g12, anticorps zgc:55637, anticorps 1110021N07Rik, anticorps AI195141, anticorps AW551338, anticorps Derlin-1, anticorps derlin-1, anticorps DER-1, anticorps DER1, anticorps RGD1311835, anticorps DERLIN-1, anticorps F17A13.150, anticorps F17A13_150, anticorps Derlin-1, anticorps derlin-1, anticorps derlin-1.1, anticorps hypothetical protein, anticorps Der1-like domain family, member 1, anticorps derlin 1, anticorps derlin 1 L homeolog, anticorps DERLIN-1, anticorps Der-1, anticorps EDI_023440, anticorps PTRG_01331, anticorps derl1, anticorps DERL1, anticorps derl1.L, anticorps Derl1, anticorps DER1

Sujet: The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Alias Symbols: DERL1, DER1, UNQ243/PRO276,

Protein Interaction Partner: HM13, TCF25, XBP1, EGFR, USP19, ZFAND2B, Vcp, PTGS2, CAV1, SYVN1, DERL2, SHH, SEL1L, SERPINA1, FAF2, ALB, APP, DERL1, EDEM1, RNF5, RHO, NGLY1, BCAP31, CFTR, UBXN6, TRAM1, APOB, CLN6, UBXN4, ERN1, ASGR2, UBE2J1, ERLIN2, UBC, HLA-A, CACNA1C, YOD1, VIMP, KPN

Protein Size: 251

ID gène: 79139

NCBI Accession: NP_077271

UniProt: Q9BUN8

Pathways: ER-Nucleus Signaling