GRPR anticorps (N-Term)

N° du produit ABIN5516040

Détail du produit anti-GRPR anticorps

Antigène: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRPR est non-conjugé

Application: Western Blotting (WB)

Séquence: FLLNLEVDHF MHCNISSHSA DLPVNDDWSH PGILYVIPAV YGVIILIGLI

Attributs du produit: This is a rabbit polyclonal antibody against GRPR. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GRPR

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GRPR

Antigène: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Autre désignation: GRPR (GRPR Produits)

Synonymes: anticorps GRPR, anticorps GRP-R, anticorps gastrin releasing peptide receptor, anticorps GRPR, anticorps Grpr

Sujet: Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.

Alias Symbols: GRPR,

Protein Size: 384

ID gène: 2925

NCBI Accession: NP_005305

UniProt: P30550