RUNX3 anticorps (C-Term)

N° du produit ABIN5516157

Détail du produit anti-RUNX3 anticorps

Antigène: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RUNX3 est non-conjugé

Application: Western Blotting (WB)

Séquence: PQNQSGPFQA NPSPYHLYYG TSSGSYQFSM VAGSSSGGDR SPTRMLASCT

Attributs du produit: This is a rabbit polyclonal antibody against RUNX3. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RUNX3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RUNX3

Antigène: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Autre désignation: RUNX3 (RUNX3 Produits)

Synonymes: anticorps runxb, anticorps RUNX3, anticorps CBFA3, anticorps frrunx3, anticorps runx3, anticorps aml2, anticorps cbfa3, anticorps pebp2ac, anticorps AML2, anticorps Cbfa3, anticorps Pebp2a3, anticorps PEBP2aC, anticorps runt-related transcription factor 3, anticorps runt related transcription factor 3, anticorps runt related transcription factor 3 L homeolog, anticorps runx3, anticorps RUNX3, anticorps runx3.L, anticorps Runx3

Sujet: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: RUNX3, AML2, CBFA3, PEBP2A3,

Protein Interaction Partner: Dlg4, UBC, PML, PIN1, NOTCH1, RBPJ, SIRT2, Cdk4, MDM2, EZH2, Vdr, SMURF2, SMURF1, HDAC9, SUV39H1, SMAD3, EP300, CBFB, SP110, HDAC5, HDAC4, HDAC2, HDAC1, TLE1, SMAD1, YAP1, SMAD5, SMAD2, PHB2,

Protein Size: 415

ID gène: 864

UniProt: Q13761