anticorps CPSQ4, anticorps SPG51, anticorps RGD1562199, anticorps 2310033A20Rik, anticorps 9930028M04Rik, anticorps AV087807, anticorps adaptor related protein complex 4 epsilon 1 subunit, anticorps adaptor-related protein complex 4, epsilon 1 subunit, anticorps adaptor-related protein complex AP-4, epsilon 1, anticorps AP4E1, anticorps Ap4e1
Sujet
This gene encodes a member of the adaptor complexes large subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is a large subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Disruption of this gene may be associated with cerebral palsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.