INSIG1 anticorps (Middle Region)
-
- Antigène Voir toutes INSIG1 Anticorps
- INSIG1 (Insulin Induced Gene 1 (INSIG1))
-
Épitope
- Middle Region
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp INSIG1 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- LAAHGAPDAD PAPRGRSAAM SGPEPGSPYP NTWHHRLLQR SLVLFSVGVV
- Purification
- Affinity purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human INSIG1
- Top Product
- Discover our top product INSIG1 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- INSIG1 (Insulin Induced Gene 1 (INSIG1))
- Autre désignation
- INSIG1 (INSIG1 Produits)
- Synonymes
- anticorps cl-6, anticorps cl6, anticorps CL-6, anticorps CL6, anticorps fb55a03, anticorps fi35b10, anticorps wu:fb55a03, anticorps wu:fi35b10, anticorps zgc:55439, anticorps 1810013C12Rik, anticorps Insig-1, anticorps INSIG-1, anticorps insulin induced gene 1, anticorps insulin induced gene 1 L homeolog, anticorps INSIG1, anticorps insig1, anticorps insig1.L, anticorps Insig1
- Sujet
-
Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: CL6, CL-6,
Protein Size: 277 - ID gène
- 3638
- NCBI Accession
- NM_005542, NP_005533
- UniProt
- O15503
- Pathways
- ER-Nucleus Signaling
-