MECOM anticorps (Middle Region)

N° du produit ABIN5517265

Détail du produit anti-MECOM anticorps

Antigène: MECOM (MDS1 and EVI1 Complex Locus (MECOM))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MECOM est non-conjugé

Application: Western Blotting (WB)

Séquence: TATSSPHSEL ESTGAILDDK EDAYFTEIRN FIGNSNHGSQ SPRNVEERMN

Attributs du produit: This is a rabbit polyclonal antibody against EVI1. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen for Anti-MECOM antibody is: synthetic peptide directed towards the Middle region of Human EVI1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MECOM

Antigène: MECOM (MDS1 and EVI1 Complex Locus (MECOM))

Autre désignation: MECOM (MECOM Produits)

Synonymes: anticorps AML1-EVI-1, anticorps EVI1, anticorps MDS1, anticorps MDS1-EVI1, anticorps PRDM3, anticorps D630039M04Rik, anticorps Evi-1, anticorps Evi1, anticorps Jbo, anticorps Mds, anticorps Mds1, anticorps Mds1-Evi1, anticorps Prdm3, anticorps Znfpr1b1, anticorps evi1, anticorps im:7140716, anticorps prdm3, anticorps evi-1, anticorps mecom, anticorps mecom-a, anticorps mecom-b, anticorps xEvi-1, anticorps evi1-B, anticorps MDS1 and EVI1 complex locus, anticorps MDS1 and EVI1 complex locus L homeolog, anticorps MDS1 and EVI1 complex locus S homeolog, anticorps MECOM, anticorps Mecom, anticorps mecom, anticorps mecom.L, anticorps mecom.S

Sujet: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.

Alias Symbols: EVI1, MDS1, PRDM3, MDS1-EVI1, AML1-EVI-1,

Protein Size: 1042

ID gène: 2122