RASGRP2 anticorps (Middle Region)

N° du produit ABIN5517288

Détail du produit anti-RASGRP2 anticorps

Antigène: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASGRP2 est non-conjugé

Application: Western Blotting (WB)

Séquence: RPPVQANPDL LSLLTVSLDQ YQTEDELYQL SLQREPRSKS SPTSPTSCTP

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RASGRP2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RASGRP2

Antigène: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Autre désignation: RASGRP2 (RASGRP2 Produits)

Synonymes: anticorps CALDAG-GEFI, anticorps CDC25L, anticorps xrasgrp2, anticorps RASGRP2, anticorps Caldaggef1, anticorps CalDAG-GEFI, anticorps rasgrp2, anticorps RAS guanyl releasing protein 2, anticorps RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog, anticorps RAS, guanyl releasing protein 2, anticorps RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog, anticorps RASGRP2, anticorps rasgrp2.S, anticorps Rasgrp2, anticorps rasgrp2.L

Sujet: The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.

Alias Symbols: CDC25L, CALDAG-GEFI

Protein Size: 609

ID gène: 10235

NCBI Accession: NM_001098670, NP_001092140

UniProt: Q7LDG7

Pathways: TCR Signaling