RPA2 anticorps (C-Term)

N° du produit ABIN5517299

Détail du produit anti-RPA2 anticorps

Antigène: RPA2 (Replication Protein A2, 32kDa (RPA2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPA2 est non-conjugé

Application: Western Blotting (WB)

Séquence: SLVAFKIMPL EDMNEFTTHI LEVINAHMVL SKANSQPSAG RAPISNPGMS

Attributs du produit: This is a rabbit polyclonal antibody against RPA2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RPA2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RPA2

Antigène: RPA2 (Replication Protein A2, 32kDa (RPA2))

Autre désignation: RPA2 (RPA2 Produits)

Synonymes: anticorps REPA2, anticorps RPA32, anticorps 153194_at, anticorps CG9273, anticorps Dmel\\CG9273, anticorps dRPA2, anticorps rpa, anticorps zgc:109822, anticorps ik:tdsubc_2g1, anticorps xx:tdsubc_2g1, anticorps repa2, anticorps rpa32, anticorps RPA2, anticorps GB13976, anticorps LOC100230445, anticorps AA409079, anticorps AI325195, anticorps AU020965, anticorps RPA34, anticorps Rf-A2, anticorps replication protein A2, anticorps Replication protein A2, anticorps replication protein A2, 32kDa, anticorps replication protein A 32 kDa subunit, anticorps RPA2, anticorps Rpa2, anticorps rpa2, anticorps LOC725418, anticorps RPA2_2

Sujet: RPA2 functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair, it does not support chromosomal DNA replication and cell cycle progression through S- phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. FUNCTION: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Required for the efficient recruitment of the DNA double-strand break repair factor RAD51 to chromatin in response to DNA damage.

Alias Symbols: RPA2, REPA2, RPA32, RPA34,

Protein Interaction Partner: HUWE1, APITD1, STRA13, FBXO18, UBC, PPP1R10, PPP1CC, POLR2E, POLA1, EXOSC10, PRDX1, NUMA1, NTHL1, NPM1, NONO, NCL, NBN, HNRNPM, PPP1R12A, MYO1E, MYO1C, MYH11, MYH10, MYH9, MYO1F, MTHFD1, MSH3, MSH2, MYO1B, MRE11A, MPG, MOV10, MNAT1, RAB8A, MAP4, CAPRIN1,

Protein Size: 358

ID gène: 6118

Pathways: Telomere Maintenance, Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA