TNFRSF11A anticorps (Middle Region)

N° du produit ABIN5518884

Détail du produit anti-TNFRSF11A anticorps

Antigène: TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Épitope: AA 235-262, Middle Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFRSF11A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 11A(TNFRSF11A) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: YRKKGKALTA NLWHWINEAC GRLSGDKE

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 11A(TNFRSF11A) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Protein Name: Tumor necrosis factor receptor superfamily member 11A

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human RANK (235-262aa YRKKGKALTANLWHWINEACGRLSGDKE), different from the related mouse sequence by seven amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur TNFRSF11A

Antigène: TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Autre désignation: TNFRSF11A (TNFRSF11A Produits)

Synonymes: anticorps RANK, anticorps RGD1563614, anticorps TNFRSF11A, anticorps Ly109, anticorps ODFR, anticorps OFE, anticorps Rank, anticorps TRANCE-R, anticorps mRANK, anticorps CD265, anticorps FEO, anticorps LOH18CR1, anticorps OPTB7, anticorps OSTS, anticorps PDB2, anticorps TRANCER, anticorps TNF receptor superfamily member 11A, anticorps TNF receptor superfamily member 11a, anticorps tumor necrosis factor receptor superfamily, member 11a, NFKB activator, anticorps Tnfrsf11a, anticorps TNFRSF11A

Sujet: Receptor Activator of Nuclear Factor κ B (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling. It is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, this gene is mapped to 18q22.1.

Synonyms: Tumor necrosis factor receptor superfamily member 11A | Osteoclast differentiation factor receptor | ODFR | Receptor activator of NF-KB | CD265 | Tnfrsf11a | Rank | Q9Y6Q6

ID gène: 8792

UniProt: Q9Y6Q6

Pathways: Signalisation NF-kappaB