GREM1 anticorps (C-Term)

N° du produit ABIN5531271

Détail du produit anti-GREM1 anticorps

Antigène: GREM1 (Gremlin 1 (GREM1))

Épitope: AA 111-139, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GREM1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GREM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the C-terminal region of human GREM1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.33 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur GREM1

Antigène: GREM1 (Gremlin 1 (GREM1))

Autre désignation: GREM1 (GREM1 Produits)

Synonymes: anticorps grem1, anticorps MGC136702, anticorps zgc:136702, anticorps GREM1, anticorps drm, anticorps pig2, anticorps dand2, anticorps ihg-2, anticorps gremlin, anticorps Cktsf1b1, anticorps Drm, anticorps Grem, anticorps ld, anticorps gremlin-1, anticorps CKTSF1B1, anticorps DAND2, anticorps DRM, anticorps GREMLIN, anticorps IHG-2, anticorps cktsf1b1, anticorps gremlin 1a, DAN family BMP antagonist, anticorps gremlin 1, DAN family BMP antagonist, anticorps gremlin 1, anticorps gremlin 1, DAN family BMP antagonist L homeolog, anticorps grem1a, anticorps GREM1, anticorps LOC662541, anticorps grem1, anticorps Grem1, anticorps grem1.L

Sujet: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 21 kDa

ID gène: 26585

UniProt: O60565

Pathways: Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location