URI1 anticorps (C-Term)

N° du produit ABIN5532036

Détail du produit anti-URI1 anticorps

Antigène: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Épitope: AA 347-376, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp URI1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This RMP (URI) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 347-376 amino acids from the C-terminal region of human RMP (URI).

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur URI1

Antigène: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Autre désignation: RMP (URI1 Produits)

Synonymes: anticorps c19orf2, anticorps C19orf2, anticorps NNX3, anticorps PPP1R19, anticorps RMP, anticorps URI, anticorps URI1 prefoldin-like chaperone L homeolog, anticorps URI1, prefoldin like chaperone, anticorps uri1.L, anticorps URI1

Sujet: The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Poids moléculaire: 60 kDa

ID gène: 8725

UniProt: O94763