Cadherin 5 anticorps (N-Term)

N° du produit ABIN5532854

Détail du produit anti-Cadherin 5 anticorps

Antigène: Cadherin 5 (CDH5)

Épitope: AA 106-134, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 5 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This VE Cadherin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the N-terminal region of human VE Cadherin.

Isotype: Ig Fraction

Information d'application

Indications d'application: For FACS starting dilution is: 1:25

For WB starting dilution is: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Cadherin 5

Antigène: Cadherin 5 (CDH5)

Autre désignation: VE Cadherin (CDH5 Produits)

Synonymes: anticorps 7B4, anticorps AA408225, anticorps Cd144, anticorps VE-Cad, anticorps VECD, anticorps VEcad, anticorps Vec, anticorps wu:fc88a07, anticorps CD144, anticorps cadherin-5, anticorps cadherin 5, anticorps CDH5, anticorps Cdh5, anticorps cdh5

Sujet: CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.

Poids moléculaire: 88 kDa

ID gène: 1003

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2