Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Immunogène
This ABCB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-746 amino acids from the C-terminal region of human ABCB7.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
ABCB7
(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))
anticorps CG7955, anticorps Dmel\\CG7955, anticorps dABCB7, anticorps GB11034, anticorps ABCB7, anticorps fc20c02, anticorps wu:fc20c02, anticorps ABC7, anticorps ASAT, anticorps Atm1p, anticorps EST140535, anticorps AA517758, anticorps AU019072, anticorps Abc7, anticorps ATP binding cassette subfamily B member 7, anticorps ATP-binding cassette sub-family B member 7, mitochondrial, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 7, anticorps ATP-binding cassette sub-family B member 7, mitochondrial-like, anticorps ABCB7, anticorps LOC412749, anticorps abcb7, anticorps LOC100367778, anticorps LOC100467128, anticorps Abcb7
Sujet
The membrane-associated protein ABCB7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.