This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Immunogène
This CYP2C8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-105 amino acids from the N-terminal region of human CYP2C8.
CYP2C8
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
2 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
CYP2C8
(Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))
anticorps CPC8, anticorps CYPIIC8, anticorps MP-12/MP-20, anticorps CYP2C74, anticorps cpc8, anticorps cyp2c8, anticorps cypiic8, anticorps mp-12/mp-20, anticorps cytochrome P450 family 2 subfamily C member 8, anticorps Cytochrome P450 2C8, anticorps cytochrome P450, family 2, subfamily C, polypeptide 8, anticorps cytochrome P450 family 2 subfamily C member 8 S homeolog, anticorps CYP2C8, anticorps CTN_0597, anticorps cyp2c8.1.S, anticorps cyp2c8.1
Sujet
CYP2C8 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol.