This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This PTPRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-316 amino acids from the Central region of human PTPRN.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
PTPRN
(Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
anticorps IA-2, anticorps IA-2/PTP, anticorps IA2, anticorps ICA512, anticorps R-PTP-N, anticorps mIA-A, anticorps mKIAA4064, anticorps Ia-2, anticorps fc43c04, anticorps ptprn, anticorps wu:fc43c04, anticorps ia-2, anticorps ia2, anticorps ica512, anticorps r-ptp-n, anticorps protein tyrosine phosphatase, receptor type N, anticorps protein tyrosine phosphatase, receptor type, N, anticorps protein tyrosine phosphatase, receptor type, Na, anticorps protein tyrosine phosphatase, receptor type N L homeolog, anticorps PTPRN, anticorps Ptprn, anticorps ptprna, anticorps ptprn.L
Sujet
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.