Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This MARK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 570-601 amino acids from the C-terminal region of human MARK3.
MARK3
Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Poulet
WB, IHC, IF, IC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
For IHC-P starting dilution is: 1:50~100
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
MARK proteins are involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2, and MAP4. MARK3 was originally identified as a marker that was induced by treatment with DNA damaging agents, and loss of MARK3 was found with carcinogenesis in the pancreas. MARK3 may be involved in cell cycle regulation, and alterations in the MARK3 gene may lead to carcinogenesis.